个人简介：白天闻，博士，副教授，硕士生导师，嘉兴大学“南湖优秀青年学者”。2016年毕业于浙江大学高分子系获学士学位，并于2021年获博士学位，同年进入嘉兴大学（原嘉兴唐人博彩论坛
）工作。目前主要从事开环聚合与计算化学研究工作，研究方向包括（1）聚氨基酸合成及应用；（2）开环聚合；（3）反应机理、各类材料性质计算。目前在Nat. Commun., Biomacromolecules, Macromolecules等国内外学术期刊上发表SCI论文70余篇，累计被引超过2100次，h因子24。主持国家科学基金青年基金项目、浙江省公益基础项目（探索一般）、嘉兴市青年人才专项和多项横向企业技术开发课题。
主持项目：
1.国家自然科学基金青年项目，2023.1-2025.12，结项
2.浙江省公益基础项目（探索一般），2026.1-，在研
3.嘉兴市青年人才专项，2024.9-，在研
学术主页：//scholar.google.com/citations?user=9PoFyxAAAAAJ
ORCiD: //orcid.org/0000-0003-1033-9756
Email: [email protected] 地址：明礼楼527
主讲课程
医药文献检索与专利、文献检索与学术写作、工程图学、制药设备与车间设计、化学制药课程设计、计算机辅助分子合成与设计、药品生产质量与管理
研究关键词
聚氨基酸、开环聚合、计算化学
代表论文
(1) Macromolecules, 2026, 59(4): 2052-2059 (SCI一区，自然指数期刊，通讯作者)
(2) Biomacromolecules, 2025, 26(12): 8382-8388 (SCI一区，通讯作者)
(3) Macromolecules, 2025, 58(8): 4238-4249 (SCI一区，自然指数期刊，通讯作者)
(4) Nature Communications, 2024,15(1): 5507 (SCI一区，Nature子刊，自然指数期刊，通讯作者)
(5) Macromolecules, 2021, 54(14): 6691-6697 (SCI一区，自然指数期刊，第一作者)
学生项目和获奖情况：
浙江省大学生化学竞赛：省二等奖（2023），省三等奖（2024，2025）
嘉兴大学大学生研究训练计划（SRT）：2023，2024
浙江省大学生科技创新活动计划（新苗人才计划）：2024
毕业生：
蒋玲玲（19届本科生）；
丁子宁、何跃新、李伟、刘永通（20届本科生）；王晓敏（20届本科生、联合指导）；
刘柏利、肖洪、叶雯煦、林洁玉（21届本科生）。
Publications
2026
1. J Liu, C Tang, Z Zhang, S Liu, L Liu, X Sun, J Ling, T Bai. Interlocked Polymerization inside Cocrystal versus Interfacial Polymerization at Solid of Racemic Leucine N-Thiocarboxyanhydride. Macromolecules 2026, 59, 2052-2059.
2. Y Lin, P Zhou, T Shen, R Yan, G Wu, J Sun, T Bai, X Ni, J Ling. Lu(OTf)3-Catalyzed Ring-Opening Polymerization of Sarcosine N-Carboxyanhydride with Quantitative Initiation Efficiency of Hydroxyl Groups. Macromolecular Rapid Communications 2026, e00835.
3. C Zhang, J Niu, M Xu, T Bai, L Lu, S Ji, P Gu, P Wang. Spatially Heterogeneous Oxygen Vacancy Engineering in Olive-Shaped In2Ox for Accelerated Sulfur Redox Kinetics and Long-Life Lithium-Sulfur Batteries. Advanced Functional Materials 2026, e21294.
2025
1. C Tang, J Liu, Z Zhang, T Bai. Thiourea-Promoted Controllable Interlocked Polymerization in Cocrystals of N-Thiocarboxyanhydrides. Biomacromolecules 2025, 26, 8382-8388.
2. F Cao, T Huang, T Bai, J Sun, J Ling, G Han. A smart "Dual-Stimuli Triggered" bioimaging nanoplatform: Combining synergistic Hypoxia/pH luminescence imaging with MRI. European Polymer Journal 2025, 114310.
3. K Zhang, W Wu, T Shen, P Zhou, T Bai, J Ling. One-Step Synthesis of Statistical Copolymers Containing Peptide, Ester, Ether, and Amine Linkages via N-Substituted Glycine N-Carboxyanhydrides and Epoxides. Macromolecules 2025, 58, 9450-9458.
4. SY Xu, TW Bai, BT Zheng, ZH Li, J Ling. Histidine N-Thiocarboxyanhydride: Direct Synthesis and Polymerization without Protection towards Well-defined Polyhistidine. Chinese Journal of Polymer Science 2025, 43, 1311-1319.
5. P Wang, C Zhang, W Li, M Xu, J Niu, T Bai, L Lu, L Zhang, G Du, S Ji. Dynamic Interface Reconstruction in Heterojunction Electrocatalysts Enables Radical-Mediated Sulfur Redox Kinetics for High-Energy Lithium-Sulfur Batteries. ACS Sustainable Chemistry and Engineering 2025, 13, 11945-11958.
6. W Li, M Xu, L Xu, L Liu, P Wang, T Bai, Y Chen, Q Long, G Du, L Zhang. Vesicular-like manganese single-atom doped Poly(1,5-Naphthalenediamine) cathode for durable bipolar zinc-organic batteries. Chemical Engineering Journal 2025, 513, 163101.
7. M Wang, Y Zhao, H Zhang, T Bai, X Wu, Y Fu. Nanofibrous membrane for red fluorescent probe of palladium: Applications in environmental analysis and cells imaging. Microchemical Journal 2025, 213, 113748.
8. S Xu, T Bai, J Ling. Understanding Acid-Promoted Polymerization of N-Phenoxycarbonyl N-Substituted Glycine: Differences among Methyl, Ethyl, and Butyl Substituents. Macromolecules 2025, 58, 4238-4249.
9. Y Lin, K Chen, T Bai, J Ling, X Ni. Carbenium-Based Cationic Ring-Opening Polymerization of CO2-Based Disubstituted delta-Valerolactone. ACS Macro Letters 2025, 14, 354-358.
10. Y Gu, H Yan, T Bai, D Rao, Y Yang, H Hu, L Li, L Guo, Y Zeng. Sensitive and selective colorimetric detection of thiophanate-methyl based on a novel Ru-Fe3O4 nanozyme with enhanced peroxidase-like activity. Microchimica Acta 2025, 192, 64.
11. M Zhou, C Liu, Y Lin, T Bai, T Ye, Z Qian, L Li, L Guo, H Liu, J Wang. Novel near-infrared fluorescent probe with large stokes shift for detection of cysteine in food sample and living cells. Food Chemistry 2025, 464, 141755.
12. X Sun, F Hua, T Bai, Y Fu. Development of red fluorescent probe for visual detection of N2H4 via nanofiber membrane and its application in environmental analysis and biological imaging. Sensors and Actuators B: Chemical 2025, 423, 136807.
13. K Chen, T Bai, YL Lin, J Ling, X Ni. Synthesis and Functionalization of Sustainable Poly(ester-co-carbonate) from Carbon Dioxide, 1,3-Butadiene, and Biosourced Diols. Macromolecules 2025, 58, 575-584.
14. T Bai, J Ling, TE Hogen-Esch. Formation mechanism of anionic isotactic polystyrene initiated by Li carbanions in cyclohexane in the presence of Na-tosylate II: a DFT calculation study. RSC Advances 2025, 15, 14809-14820.
15. M Hou, M Jia, R Qi, Z Zhang, L He, T Bai, C Bao, G Qiu. Ferric nitrene-promoted anti-Markovnikov ring-opening of epoxides and nucleophilic functionalization of benzylic C-H bonds under photo-irradiation. Chemical Communications 2025, 61, 1435-1438.
2024
1. Y Wu, X Wang, T Bai, Y Fu. Dual-channel fluorescent probe for detecting SO2 and Hg2+, and dynamic imaging SO2 under Cd2+ in alfalfa (Medicago sativa). Analytica Chimica Acta 2024, 1332, 343353.
2. S Xie, S Tang, M Hou, W Xie, M Guan, T Bai, L He, G Qiu. Photoredox/Iron dual-catalysis-enabled [4+2] cyclization of acyl nitrene with alkynes. Organic Letters 2024, 26, 11134-11139.
3. Y Lin, K Chen, T Bai, J Ling, X Ni. Isomerization Cationic Ring-Opening Polymerization of CO2-Based Disubstituted-delta-Valerolactone. ChemRxiv 2024, 2024, 2024.0902.
4. M Zhou, Y Lin, T Bai, T Ye, Y Zeng, L Li, Z Qian, L Guo, H Liu, J Wang. An activated near-infrared fluorescent probe with large Stokes shift for discrimination of bio-thiols. Sensors and Actuators B: Chemical 2024, 414, 135994.
5. Q Yu, Y Mao, T Bai, T Ye, Z Peng, K Chen, L Guo, L Li, J Wang. Near-infrared Rhodols-based fluorescent probe with large Stokes shift for tracking of H2S in food spoilage and living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2024, 315, 124250.
6. B Zheng, L Zhong, X Wang, P Lin, Z Yang, T Bai, H Shen, H Zhang. Structural evolution during inverse vulcanization. Nature Communications 2024, 15, 5507.
7. M Zhao, W Lai, B Li, T Bai, C Liu, Y Lin, S An, L Guo, L Li, J Wang. NIR-II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization. Angewandte Chemie International Edition 2024, 63, e202403968.
8. T Shen, T Bai, Y Chen, M Zhu, L Li, J Ling. Easy Access to Ultrahigh-Molecular Weight Poly(1,3-dioxolane) by Rare Earth Triflates. Macromolecules 2024, 57, 5271-5278.
9. M Hou, Z Zhang, X Lai, Q Zong, M Ren, T Bai, G Qiu. Photo-Induced Electrophilic Aromatic Substitution of Ferric Acyl Nitrene. Synthesis 2024, 56, 496-506.
10. S An, Y Lin, T Ye, T Bai, D He, L Guo, Z Qian, L Li, H Liu, J Wang. An extra-large Stokes shift near-infrared fluorescent probe for specific detection and imaging of cysteine. Talanta 2024, 267, 125247.
11. Y Sun, Y Mao, T Bai, T Ye, Y Lin, F Wang, L Li, L Guo, H Liu, J Wang. An activated near-infrared mitochondrion-targetable fluorescent probe for rapid detection of NADH. Chemical Communications 2024, 60, 5932-5935.
12. J Wang, P Zhou, T Shen, S Xu, T Bai, J Ling. Glycine N-Thiocarboxyanhydride: A Key to Glycine-Rich Protein Mimics. ACS Macro Letters 2024, 12, 1466-1471.
2023
1. K Zhang, T Bai, J Ling. Iron(III) triflate as a green catalyst for janus polymerization to prepare block polyesters. Macromolecules 2023, 56, 7389-7395.
2. S Yin, J Qu, P Kannan, L Lu, F Zhou, V Linkov, T Bai, H Cao, P Wang, S Ji. Indium/cobalt nanoparticles impregnated porous nitrogen-doped carbon matrix as a 3D sulfur host for lithium polysulfide adsorption-desorption and catalytic conversion in lithium-sulfur batteries. Composites Part B: Engineering 2023, 264, 110905.
3. J Zhang, T Bai, W Liu, M Li, Q Zang, C Ye, JZ Sun, Y Shi, J Ling, A Qin. All-organic polymeric materials with high refractive index and excellent transparency. Nature Communications 2023, 14, 3524.
4. X Wang, Y Lin, X Sun, Y Wu, H Miao, J Chu, T Bai, Y Fu. A lysosomal targeted fluorescent probe based on BODIPY for monitoring NO in living cells and zebrafish imaging. Sensors and Actuators B: Chemical 2023, 383, 133592.
5. R Qi, T Bai, S Tang, M Hou, Z Zhang, W Xie, Y Deng, H Zhou, G Qiu. Solvent-promoted photochemical carbonylation of benzylic C-H bonds under iron catalysis. Organic and Biomolecular Chemistry 2023, 21, 5382-5386.
6. Y Zhao, T Bai, Y Liu, Y Lv, Z Zhou, Y Shen, L Jiang. Encapsulation of volatile monoterpene fragrances in mesoporous organosilica nanoparticles and potential application in fruit preservation. Nanomaterials 2023, 13, 104.
2022
1. K Chen, Z Zhu, T Bai, Y Mei, T Shen, J Ling, X Ni. A Topology-Defined Polyester Elastomer from CO2 and 1,3-Butadiene: A One-Pot-One-Step "Scrambling Polymerizations" Strategy. Angewandte Chemie International Edition 2022, 61, e202213028.
2. J Zhang, T Bai, W Liu, Q Zang, C Ye, JZ Sun, Y Shi, J Ling, A Qin, BZ Tang. All-Organic Polymeric Materials with Extraordinarily High Refractive Index and Excellent Transparency. ChemRxiv 2022, 2022, 2022.1028.
3. B Song, T Bai, D Liu, R Hu, D Lu, A Qin, J Ling, BZ Tang. Visualized Degradation of CO2-Based Unsaturated Polyesters toward Structure-Controlled and High-Value-Added Fluorophores. CCS Chemistry 2022, 4, 237-249.
4. T Cheng, T Bai, D Huang, A Qin, J Ling, BZ Tang. Stereochemistry-Tunable Isocyanide-Based Polymerization. Macromolecules 2022, 54, 11289-11295.
2021
1. Q Cai, T Bai, H Zhang, X Yao, J Ling, W Zhu. Catalyst-free synthesis of polyesters via conventional melt polycondensation. Materials Today 2021, 51, 155-164.
2. B Zheng, T Bai, X Tao, J Ling. An inspection into multifarious ways to synthesize poly(amino acid)s. Macromolecular Rapid Communications 2021, 42, 2100453.
3. H Yu, Z Tong, T Bai, Z Mao, X Ni, J Ling. Self-crosslinked poly-L-ornithine and poly-L-arginine networks: Synthesis, characterization, pH-responsibility, biocompatibility, and AIE-functionality. Journal of Applied Polymer Science 2021, 138, 50802.
4. S Yue, T Bai, S Xu, T Shen, J Ling, X Ni. Ring-Opening Polymerization of CO2-Based Disubstituted delta-Valerolactone toward Sustainable Functional Polyesters. ACS Macro Letters 2021, 10, 1055-1060.
5. T Bai, P Zhou, Z Li, B Zheng, J Ling. Seeding crystals, harvesting polypeptides: preparing long chiral-sequence controlled polypeptides by interlocked polymerization in cocrystals (iPiC) of N-thiocarboxyanhydride. Macromolecules 2021, 54, 6691-6697.
6. CN Zhu, T Bai, H Wang, J Ling, F Huang, W Hong, Q Zheng, ZL Wu. Dual-encryption in a shape-memory hydrogel with tunable fluorescence and reconfigurable architecture. Advanced Materials 2021, 33, 2102023.
7. T Bai, B Zheng, J Ling. Density functional theory studies on the synthesis of poly(alpha-amino acid)s via the amine-mediated ring opening polymerizations of N-carboxyanhydrides and N-thiocarboxyanhydrides. Frontiers in Chemistry 2021, 9, 645949.
2020
1. B Zheng, T Bai, J Ling, J Sun. Direct N-substituted N-thiocarboxyanhydride polymerization towards polypeptoids bearing unprotected carboxyl groups. Communications Chemistry 2020, 3, 144.
2. B Song, T Bai, D Liu, R Hu, D Lu, J Ling, A Qin, BZ Tang. Visualized Degradation of Poly(alkynoate)s Toward Diols and Structure Controlled Multifunctional N-Heterocyclic Compounds. ChemRxiv 2020, 2020, 2020.1014.
3. X Chen, T Bai, R Hu, B Song, L Lu, J Ling, A Qin, BZ Tang. Aroylacetylene-based amino-yne click polymerization toward nitrogen-containing polymers. Macromolecules 2020, 53, 2516-2525.
4. T Bai, B Shen, D Cai, Y Luo, P Zhou, J Xia, B Zheng, K Zhang, R Xie, X Ni. Understanding ring-closing and racemization to prepare alpha-amino acid NCA and NTA monomers: a DFT study. Physical Chemistry Chemical Physics 2020, 22, 14868-14874.
5. H Qiu, MI Shah, T Bai, L Jiang, J Ling. Zwitterionic copolymerization of gamma-butyrolactone with 3,3-bis(chloromethyl)oxacyclobutane catalyzed by scandium triflates. Polymer Chemistry 2020, 11, 1845-1851.
2019
1. S Cai, T Bai, H Chen, W Fang, Z Xu, H Lai, T Huang, H Xu, X Chu, J Ling. Heavy water enables high-voltage aqueous electrochemistry via the deuterium isotope effect. The Journal of Physical Chemistry Letters 2019, 11, 303-310.
2. H Qiu, Y Li, T Bai, J Ling. Janus Polymerization: A Novel Approach towards Topology Design. Acta Polymerica Sinica 2019, 50, 1133-1145.
3. S Liu, T Bai, K Ni, Y Chen, J Zhao, J Ling, X Ye, G Zhang. Biased Lewis Pairs: A General Catalytic Approach to Ether-Ester Block Copolymers with Unlimited Ordering of Sequences. Angewandte Chemie International Edition 2019, 58, 15478-15487.
4. TW Bai, XF Ni, J Ling, ZQ Shen. Mechanism of Janus polymerization: a DFT study. Chinese Journal of Polymer Science 2019, 37, 990-994.
5. J Wang, T Bai, Y Chen, C Ye, T Han, A Qin, J Ling, BZ Tang. Palladium/Benzoic Acid-Catalyzed Regio- and Stereoselective Polymerization of Internal Diynes and Diols through C(sp3)-H Activation. ACS Macro Letters 2019, 8, 1068-1074.
6. B Song, T Bai, X Xu, X Chen, D Liu, J Guo, A Qin, J Ling, BZ Tang. Multifunctional Linear and Hyperbranched Five-Membered Cyclic Carbonate-Based Polymers Directly Generated from CO2 and Alkyne-Based Three-Component Polymerization. Macromolecules 2019, 52, 5546-5554.
7. Z Yang, T Bai, J Ling, Y Shen. Hydroxyl-tolerated polymerization of N-phenoxycarbonyl alpha-amino acids: A simple way to polypeptides bearing hydroxyl groups. Journal of Polymer Science Part A: Polymer Chemistry 2019, 57, 907-916.
8. T Bai, J Ling. Polymerization rate difference of N-alkyl glycine NCAs: Steric hindrance or not?. Biopolymers 2019, 110, e23261.
9. H Xu, T Bai, H Chen, F Guo, J Xi, T Huang, S Cai, X Chu, J Ling, W Gao. Low-cost AlCl3/Et3NHCl electrolyte for high-performance aluminum-ion battery. Energy Storage Materials 2019, 17, 38-45.
10. B Song, T Bai, X Xu, X Chen, D Liu, J Guo, A Qin, J Ling, BZ Tang. Multifunctional Linear and Hyperbranched Five-Membered Cyclic Carbonate-Based Polymers Directly Generated from CO2 and Alkyne-Based Three-Component Polymerization. 2019.
11. Z Li, Z Yang, T Bai, J Ling. One-step synthesis and regioselective polymerization of Nalpha, Ndelta-bisphenoxycarbonyl-L-ornithine. Polymer Chemistry 2019, 10, 1062-1066.
12. CN Zhu, T Bai, H Wang, W Bai, J Ling, JZ Sun, F Huang, ZL Wu, Q Zheng. Single chromophore-based white-light-emitting hydrogel with tunable fluorescence and patternability. ACS Applied Materials and Interfaces 2019, 10, 39343-39352.
2018
1. B Zheng, T Bai, X Tao, H Schlaad, J Ling. Identifying the Hydrolysis of Carbonyl Sulfide as a Side Reaction Impeding the Polymerization of N-Substituted Glycine N-Thiocarboxyanhydride. Biomacromolecules 2018, 19, 4263-4269.
2. X Tao, B Zheng, T Bai, MH Li, J Ling. Polymerization of N-Substituted Glycine N-Thiocarboxyanhydride through Regioselective Initiation of Cysteamine: A Direct Way toward Thiol-Capped Polypeptoids. Macromolecules 2018, 51, 4494-4501.
3. XQ Chen, X Yao, T Bai, J Ling, WJ Xiao, J Wang, SC Wu, LN Liu, G Xie. Donor-acceptor photovoltaic polymers based on 1,4-dithienyl-2,5-dialkoxybenzene with intramolecular noncovalent interactions. Journal of Polymer Science Part A: Polymer Chemistry 2018, 56, 689-698.
4. J Zhang, M Zhang, T Bai, X Ni, Z Shen. Synthesis and characterization of heterobimetallic organo rare earth complexes bearing aryloxide-N-heterocyclic carbene ligands. Journal of Organometallic Chemistry 2018, 843, 1-6.
2017
1. Y Shi, T Bai, W Bai, Z Wang, M Chen, B Yao, JZ Sun, A Qin, J Ling. Phenol-yne Click Polymerization: An Efficient Technique to Facilely Access Regio-and Stereoregular Poly(vinylene ether ketone)s. Chemistry-A European Journal 2017, 23, 10725-10731.
2. T Bai, J Ling. NAM-TMS Mechanism of alpha-Amino Acid N-Carboxyanhydride Polymerization: A DFT Study. The Journal of Physical Chemistry A 2017, 121, 4588-4593.
3. X Tao, B Zheng, T Bai, B Zhu, J Ling. Hydroxyl Group Tolerated Polymerization of N-Substituted Glycine N-Thiocarboxyanhydride Mediated by Aminoalcohols: A Simple Way to alpha-Hydroxyl-omega-peptides. Macromolecules 2017, 50, 3066-3077.
4. B He, H Su, T Bai, Y Wu, S Li, M Gao, R Hu, Z Zhao, A Qin, J Ling. Spontaneous amino-yne click polymerization: a powerful tool toward regio-and stereospecific poly(beta-aminoacrylate)s. Journal of the American Chemical Society 2017, 139, 5437-5443.
5. Z Xie, J Ge, H Zhang, T Bai, S He, J Ling, H Sun, Q Zhu. A highly selective two-photon fluorogenic probe for formaldehyde and its bioimaging application in cells and zebrafish. Sensors and Actuators B: Chemical 2017, 241, 1050-1056.
6. Y Li, T Bai, Y Li, J Ling. Branched Polytetrahydrofuran and Poly(tetrahydrofuran-co-epsilon-caprolactone) Synthesized by Janus Polymerization: A Novel Self-Healing Material. Macromolecular Chemistry and Physics 2017, 218, 1600450.
